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The Sympathetic Nervous System01:25

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Electroacupuncture for Reflex Sympathetic Dystrophy after Stroke: A Meta-Analysis.

Xuqiang Wei1, Liyun He2, Jia Liu2

  • 1College of Acupuncture and Orthopedic, Hubei University of Traditional Chinese Medicine, Wuhan, Hubei, P.R. China; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, P.R. China.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|March 4, 2019
PubMed
Summary

Electroacupuncture (EA) effectively alleviates pain and improves limb function in Reflex Sympathetic Dystrophy (RSD) patients. This therapy enhances daily living activities and reduces swelling, offering a promising treatment option.

Keywords:
Electroacupuncturemeta-analysispoststrokereflex sympathetic dystrophyreview

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Integrative Medicine

Background:

  • Reflex Sympathetic Dystrophy (RSD) is a common complication following stroke and cerebral injuries.
  • Current treatment options for RSD lack both safety and efficacy.
  • Electroacupuncture (EA) presents a potential therapeutic approach, but supporting evidence is limited.

Purpose of the Study:

  • To systematically evaluate the efficacy and safety of Electroacupuncture (EA) for treating Reflex Sympathetic Dystrophy (RSD).
  • To compare EA with conventional rehabilitation therapy in improving pain, motor function, and daily living activities in RSD patients.

Main Methods:

  • A comprehensive literature search was conducted across multiple databases (e.g., Cochrane Library, MEDLINE, Embase) up to July 20, 2018.
  • Included randomized controlled trials (RCTs) comparing EA with conventional rehabilitation for RSD treatment.
  • Key outcomes assessed included visual analog scale (VAS) for pain, Fugl-Meyer upper limb motor function, Barthel index, and hand swelling score.

Main Results:

  • The meta-analysis included 13 studies with 1040 RSD patients, with follow-up periods ranging from 2 to 6 weeks.
  • EA demonstrated statistically significant improvements in pain relief (WMD = -1.122, P=.000) and motor function (WMD = 6.039, P=.000) compared to conventional therapy.
  • EA also showed significant benefits in enhancing activities of daily living (WMD = 12.170, P<.00011) and reducing limb swelling (WMD = -0.800, P=.000).

Conclusions:

  • This meta-analysis provides evidence supporting the positive effects of EA in alleviating pain, improving limb dysfunction, and enhancing daily living activities in RSD patients.
  • The findings suggest EA is a beneficial adjunct or alternative to conventional rehabilitation for RSD.
  • Further high-quality RCTs are recommended to optimize EA treatment protocols due to moderate study quality and high heterogeneity.