Meningococcal C vaccine coverage in France in infants, children, and adolescents

J Gaudelus1, R Cohen2, B Leboucher3

  • 1Service de pédiatrie, hôpital Jean-Verdier, 93140 Bondy, France; Université Paris-XIII, 93017 Bobigny, France.

Insights

Meningococcal C vaccination coverage in France remains insufficient for herd immunity, necessitating improved strategies. A new recommendation for infant vaccination at 5 months shows promise for increasing coverage and preventing disease.

Area of Science:

  • Public Health
  • Epidemiology
  • Vaccinology

Background:

  • Meningococcal C (MenC) vaccination was implemented in France in 2010 to reduce invasive meningococcal C disease (IMDC) incidence via herd immunity.
  • The Vaccinoscopie survey monitors vaccination coverage rates (VCRs) in children.

Purpose of the Study:

  • To assess MenC vaccination coverage rates and parental perceptions in France.
  • To evaluate the impact of the 2017 vaccine calendar update recommending MenC vaccination for infants.

Main Methods:

  • Annual online survey using self-administered questionnaires completed by mothers.
  • Data collected in 2017 from 4500 mothers on child vaccinations.
  • Analysis of VCRs across different age groups and influencing factors.

Main Results:

  • 77%-84% of mothers found MenC vaccination indispensable or useful; fear of adverse effects was a key barrier.
  • VCRs were 77% (24-35 months), 79% (6 years), and 50% (14-15 years).
  • Six months post-recommendation, 43% of infants received the MenC vaccine by 6 months.

Conclusions:

  • Current MenC VCRs are insufficient to achieve herd immunity in France.
  • Over 100 deaths could have been avoided between 2011-2017 with optimal VCRs.
  • The new 5-month infant recommendation and 2018 mandatory vaccination are expected to significantly reduce IMDC incidence.
Abstract

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