Related Experiment Video For Central pancreatectomy

Updated: Jan 28, 2026

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Published on: February 2, 2024

Central pancreatectomy for early-stage pancreatic ductal adenocarcinoma: a single-center case-control study

Hao Gao^1,2, Tongtai Liu^1,2, Guangfu Wang^1,2

¹Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.

Langenbeck'S Archives of Surgery

|March 4, 2019

Abstract

Purpose:

Central pancreatectomy (CP) has been applied for treating benign and low-grade malignant tumors in pancreatic neck, but studies regarding CP for pancreatic ductal adenocarcinoma (PDAC) are quite limited. We aimed to investigate the role of central pancreatectomy in the treatment of PDAC in the neck of the pancreas.

Methods:

Patients who underwent CP at our hospital between 2009 and 2016 were identified. Patients treated by distal pancreatectomy (DP) were matched according to the tumor size, location, and staging. The surgical and survival outcomes were compared between the CP and DP groups.

Results:

Nine patients had CP. Five (56%) had postoperative complications and three (33%) had clinically significant (grade B + C) fistula. No significant difference was found between the CP and DP groups for the rate of overall morbidity, pancreatic fistula, reoperation, and readmission. Tumor size was smaller in the CP group compared to the DP group. The mortality of both groups was zero. The median postoperative survival was similar between the two groups (20.4 months for CP vs 19.4 months for DP, P = 0.842).

Conclusions:

CP is safe for patients with small PDAC at the neck of the pancreas. Considering the good preservation of pancreatic endocrine and exocrine functions, CP could be considered as an alternative procedure for single small PDAC in pancreatic neck.

Keywords:

Central pancreatectomy Morbidity Pancreatic ductal adenocarcinoma Pancreatic fistula Postoperative survival

More Related Videos

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Published on: November 19, 2019

Application of End-to-end Anastomosis in Robotic Central Pancreatectomy

Application of End-to-end Anastomosis in Robotic Central Pancreatectomy

Published on: June 2, 2018

Related Concept Videos

Brainstem: Control Centers of Medulla

Brainstem: Control Centers of Medulla

The medulla oblongata is a crucial part of the brainstem responsible for controlling various autonomic and involuntary functions. It contains several nuclei, including the olivary, cuneate, gracile, and solitary nuclei.
Olivary Nucleus
The olivary nucleus, or inferior olivary nucleus, is located within the ventrolateral part of the medulla oblongata. It is primarily involved in motor coordination and motor learning. The olivary nucleus receives input from the spinal cord, cerebellum, and motor...

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...

Lattice Centering and Coordination Number

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...

Measures of Central Tendency

Measures of Central Tendency

The "center" of a data set is also a way of describing location. The two most widely used measures of the "center" of the data are the mean (average) and the median. The words "mean" and "average" are often used interchangeably. The substitution of one word for the other is common practice. The technical term is "arithmetic mean" and "average" is technically a center location. However, in practice among non-statisticians,...

The Central Dogma

The Central Dogma

Center of Gravity

Center of Gravity

The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...

Keywords:

Central pancreatectomy Morbidity Pancreatic ductal adenocarcinoma Pancreatic fistula Postoperative survival

Articles linked to this work by shared authors, journal, and citation graph.

Suggestive causal associations between 17 autoimmune diseases and pancreatitis: A two-sample Mendelian randomization study.

Medicine·2026

Celiac axis stenosis as an overlooked extrapancreatic predictor of fistula after pancreaticoduodenectomy.

Surgical endoscopy·2026

Synergistic promotion of conjugative transfer of antibiotic resistance genes by triclosan: Bridging Two-Component system and quorum sensing.

Journal of hazardous materials·2026

Revisiting down syndrome through the lens of interferonopathy and innate immune dysregulation.

Frontiers in immunology·2026

Differential effects of conventional and biodegradable microplastics on carbon and nitrogen transformation and greenhouse gas emissions in Cd-contaminated riparian sediments: Responses of microbial community structure.

Water research·2026

Molten Salt Assisted Carbon Nitride Overcomes Inherent Photocatalytic Limitations: Unique Characteristics for High-Efficiency Light-Driven Energy Production.

Small (Weinheim an der Bergstrasse, Germany)·2026

See all related articles