Related Experiment Video
Updated: Jan 28, 2026

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
A study on the preparation of chitosan-tripolyphosphate nanoparticles and its entrapment mechanism for egg white
Zhiyang Du1, Jingbo Liu1, Ting Zhang1
1Jilin Key Laboratory of Nutrition and Functional Food, Jilin University, Changchun 130062, People's Republic of China.
Abstract:
The entrapment of peptides can effectively improve their bioavailability and commercial application. This research sought to investigate the mechanism of entrapment of egg white derived peptides (EWDP) loaded in chitosan-tripolyphosphate (CS-TPP) nanoparticles (NPs). It was shown that CS molecular weight (MW), pH, CS-TPP mass ratio and CS concentration can all affect the size, polydispersity index and zeta potential of CS-TPP NPs. Moreover, these factors, as well as different MW and CS mass ratio of peptides also had an influence on entrapment efficiency (EE). Furthermore, peptides influenced the zeta potential after they were loaded in the CS-TPP NPs. This suggested that the peptide charged groups were in different locations relative to the CS-TPP NPs surfaces. FTIR analysis indicated that the peptides interacted with CS-TPP NPs through strong hydrogen bonds and electrostatic interactions. These findings are important for designing delivery systems used for commercial production of entrapped peptides with enhanced attributes.
More Related Videos
Related Concept Videos
Peptide Bonds
Preparation of Aldehydes and Ketones from Carboxylic Acid Derivatives
Carboxylic acid derivatives like acid chlorides and esters are more easily reducible than the corresponding acids. The derivatives reduce in the presence of mild reducing agents to give aldehydes. Aldehydes can also be prepared by Rosenmund reduction, that is, the reduction of...
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Mechanism
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Reaction Mechanisms
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
The Quantum-Mechanical Model of an Atom

