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Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Imaging Studies I: CT and MRI01:14

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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
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Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
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Response Surface Methodology01:16

Response Surface Methodology

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Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
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Imaging Studies for Cardiovascular System V: CT01:28

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Radiomics in Oncological PET/CT: a Methodological Overview.

Seunggyun Ha1,2, Hongyoon Choi2, Jin Chul Paeng2

  • 11Radiation Medicine Research Institute, Seoul National University College of Medicine, Seoul, South Korea.

Nuclear Medicine and Molecular Imaging
|March 5, 2019
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Radiomics, a medical imaging analysis, quantifies intratumoral heterogeneity from PET scans. Despite challenges in standardization, it shows promise for personalized cancer medicine.

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FDG PET/CTIntratumoral heterogeneityOncologyRadiomicsTexture analysis

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Area of Science:

  • Medical Imaging
  • Computer Vision
  • Oncology

Background:

  • Radiomics analyzes medical images using computer vision.
  • Metabolic radiomics specifically examines molecular metabolism patterns in PET images.
  • A key goal is measuring intratumoral heterogeneity to develop image-based models for patient management.

Purpose of the Study:

  • To outline the radiomics workflow for texture analysis.
  • To highlight the impact of various parameters on results.
  • To discuss challenges and future potential in personalized oncology.

Main Methods:

  • The radiomics workflow involves imaging, preprocessing (segmentation, quantization), quantification (texture feature extraction), and analysis (statistics, machine learning).
  • Texture analysis is a core component of the radiomics workflow.
  • Consideration of statistical issues like multiple comparisons and high dimensionality is crucial.

Main Results:

  • Parameters and conditions at each step significantly affect radiomics results.
  • Methodological standardization and image quality harmonization are critical challenges.
  • Statistical considerations are vital for robust analysis.

Conclusions:

  • Radiomics methodology faces challenges, including standardization and harmonization.
  • Despite current issues, radiomics is anticipated to be valuable in personalized oncology.
  • Further development is needed to overcome methodological hurdles for clinical utility.