restfulSE: A semantically rich interface for cloud-scale genomics with Bioconductor
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A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
Published on: April 12, 2018
Shweta Gopaulakrishnan1, Samuela Pollack1,2, B J Stubbs1
1Channing Division of Network Medicine, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Abstract:
Bioconductor's SummarizedExperiment class unites numerical assay quantifications with sample- and experiment-level metadata. SummarizedExperiment is the standard Bioconductor class for assays that produce matrix-like data, used by over 200 packages. We describe the restfulSE package, a deployment of this data model that supports remote storage. We illustrate use of SummarizedExperiment with remote HDF5 and Google BigQuery back ends, with two applications in cancer genomics. Our intent is to allow the use of familiar and semantically meaningful programmatic idioms to query genomic data, while abstracting the remote interface from end users and developers.
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