The Hertfordshire Cohort Study: an overview
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Updated: Jan 28, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Holly E Syddall1, Shirley J Simmonds1, Sarah A Carter1
1MRC Lifecourse Epidemiology Unit, Southampton, Hampshire, SO16 6YD, UK.
Abstract:
The Hertfordshire Cohort Study is a nationally unique study of men and women born in the English county of Hertfordshire in the early part of the 20 th century. Records that detail their health in infancy and childhood have been preserved, their sociodemographic, lifestyle, medical and biological attributes have been characterised in later life, and routinely collected data on their hospital use and mortality have been acquired. This paper provides an overview of the study since its inception in the 1980s, including its methods, findings, and plans for its future.
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