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Boceprevir-induced Herpes Zoster.

Ayşegul Babalı1, Basak Cakal1, Alpaslan Tanoglu2

  • 1Department of Gastroenterology, Ankara Training and Research Hospital, Ankara, Turkey.

Euroasian Journal of Hepato-Gastroenterology
|March 5, 2019
PubMed
Summary

Reactivation of varicella zoster virus (VZV) causes herpes zoster. This report details an extremely rare case of Boceprevir-induced herpes zoster in a patient undergoing treatment for chronic hepatitis C.

Keywords:
BoceprevirHerpes zosterInfection.

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Area of Science:

  • Hepatology
  • Virology
  • Dermatology

Background:

  • Herpes zoster, caused by varicella zoster virus (VZV) reactivation, leads to painful nerve inflammation and skin lesions.
  • Boceprevir is a protease inhibitor utilized in treating chronic hepatitis C.
  • The co-occurrence of Boceprevir and herpes zoster is exceptionally rare.

Observation:

  • This case report describes a patient with chronic hepatitis C who developed herpes zoster.
  • The herpes zoster infection was associated with the use of Boceprevir.

Findings:

  • The patient presented with herpes zoster infection during Boceprevir therapy for chronic hepatitis C.
  • This highlights a rare adverse event linked to Boceprevir treatment.

Implications:

  • Clinicians should be aware of the potential for Boceprevir-induced herpes zoster in hepatitis C patients.
  • Further investigation into the mechanism of Boceprevir's association with VZV reactivation may be warranted.