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The relationship between allergy and chronic rhinosinusitis.
Sonya Marcus1, Lauren T Roland1, John M DelGaudio1
1Department of Otolaryngology-Head & Neck Surgery Emory University School of Medicine Atlanta Georgia U.S.A.
Laryngoscope Investigative Otolaryngology
|March 5, 2019
Summary
The link between chronic rhinosinusitis (CRS) and allergy is unclear, with limited evidence supporting a general association. However, specific CRS types, like allergic fungal rhinosinusitis, show a strong connection to allergy.
Area of Science:
- Otolaryngology
- Immunology
- Allergy Research
Background:
- Chronic rhinosinusitis (CRS) is a common condition often presumed to be linked with allergies.
- The precise relationship between CRS and allergic conditions requires further clarification.
Purpose of the Study:
- To review and synthesize current scientific evidence on the association between chronic rhinosinusitis and allergy.
- To investigate specific subtypes of CRS that may exhibit a stronger link to allergic diseases.
Main Methods:
- A comprehensive literature review was conducted.
- Analysis focused on studies examining the relationship between CRS and allergy.
Main Results:
- Evidence for a general association between CRS and allergy is inconclusive and derived from heterogeneous, often retrospective, studies.
- Allergic fungal rhinosinusitis and central compartment atopic disease are CRS subtypes with a demonstrated strong association with allergy.
Conclusions:
- The overall evidence linking CRS and allergy is not definitive.
- Understanding distinct CRS endotypes is crucial for determining specific associations with allergy.
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