Related Experiment Video
Updated: Jan 28, 2026
05:23
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
20.3K
Lessons Learned from Building a Pediatric-to-Adult Sickle Cell Transition Program
Wally R Smith1, India Y Sisler1, Shirley Johnson1
1From the Department of Internal Medicine, Division of General Internal Medicine, Department of Pediatrics, Division of Pediatric Hematology/Oncology and Department of Psychology, Virginia Commonwealth University, Richmond, and Department of Hematology/Oncology, University of California, San Francisco Benioff Children's Hospital, San Francisco.
Southern Medical Journal
|March 5, 2019
Summary
Developing a structured program using six core elements significantly improved the transition of young people with sickle cell disease (SCD) to adult healthcare, overcoming common barriers.
Area of Science:
- Pediatric Healthcare
- Transition Medicine
- Hematology
Background:
- Effective transition from pediatric to adult healthcare is crucial for young people with sickle cell disease (SCD).
- Current transition processes often face significant barriers, impacting patient outcomes.
- Six core elements are recognized as essential for successful care transitions.
Purpose of the Study:
- To assess the development and implementation of a program designed to improve SCD care transitions.
- To evaluate the effectiveness of a structured approach based on six core elements.
Main Methods:
- A program was developed and implemented at Virginia Commonwealth University utilizing six core elements.
- Key aspects assessed included age, independent living skills, and patient readiness for adult care.
- Transfer success and patient retention rates were analyzed.
Main Results:
- The program's development and implementation over five years provided valuable insights.
- Individual differences in age and grade, independent living skills, and feelings about transitioning were assessed.
- Analysis of assessment scales and transfer success metrics informed program refinement.
Conclusions:
- A dedicated, flexible care team is vital for overcoming barriers in SCD care transitions.
- The program demonstrated the feasibility of implementing a structured transition process.
- Lessons learned highlight the importance of a comprehensive, patient-centered approach.
More Related Videos
Related Concept Videos
01:33Adult Stem Cells
33.8K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
33.8K
02:31Phase Transitions
23.1K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
23.1K
02:58Properties of Transition Metals
29.7K
Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
29.7K
01:58Cooperative Allosteric Transitions
8.7K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
8.7K
02:39Phase Transitions: Vaporization and Condensation
21.0K
The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules...
21.0K
02:33Phase Transitions: Sublimation and Deposition
20.0K
Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
20.0K