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Updated: Jan 28, 2026

Author Spotlight: Exploring the Fermentation Microbiome Through Next-Generation Sequencing
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Wine and grape marc spirits metabolomics.

Dimitra Diamantidou1, Anastasia Zotou1, Georgios Theodoridis2

  • 1Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

Metabolomics : Official Journal of the Metabolomic Society
|March 5, 2019
PubMed
Summary

Metabolomics, using mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy, enhances understanding of wine and grape marc spirits. While no single method is perfect, these techniques are crucial for quality control and authenticity studies.

Keywords:
GC–MSGrape marc spiritsLC–MSMetabolic profilingNMRWine

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Area of Science:

  • Analytical Chemistry
  • Food Science
  • Biochemistry

Background:

  • Metabolomics offers a holistic view of wine and grape marc spirits, aiding in process monitoring and quality improvement.
  • Mass spectrometry (MS)-based and nuclear magnetic resonance (NMR) spectroscopy are vital analytical tools in metabolomics.

Purpose of the Study:

  • To review the latest metabolomics approaches for wine and grape marc spirits.
  • To focus on MS-based and NMR spectroscopic analytical techniques.

Main Methods:

  • Literature review of metabolomic studies on wine and grape marc spirits published up to 2017.
  • Identification of articles using keywords 'metabolomics', 'wine', and 'grape marc spirits' and reference list analysis.

Main Results:

  • Metabolomics approaches have significantly advanced knowledge of wine and grape marc spirits.
  • No single analytical platform can comprehensively analyze all metabolites in one go.

Conclusions:

  • Authentication and quality control require caution due to influencing factors.
  • NMR spectroscopy and MS-based strategies are key analytical methods in metabolomics.
  • Authenticity, traceability, and health implications are primary research drivers.