Related Experiment Video
Updated: Jan 28, 2026

Terminal H-reflex Measurements in Mice
Published on: June 16, 2022
Reduction of oculocardiac reflex with Tetracaine eye drop in strabismus surgery
Mojtaba Rahimi Varposhti1, Darioush Moradi Farsani1, Keyvan Ghadimi2
1a Department of Anesthesiology, Faculty of Medicine , Isfahan University of Medical Sciences , Isfahan.
Introduction:
Recently, to reduce the incidence of oculocardiac reflex (OCR) in strabismus surgery, retrobulbar block and anticholinergic drugs or local anesthesia are also used. The present study evaluated the effects of Tetracaine eye drop as a topical nerve blocker on OCR during strabismus surgery.
Methods And Materials:
In this randomized trial, 70 strabismus surgery candidates were randomly divided into placebo or synthetic teardrop (E) and Tetracaine eye drop (T) groups, so 3 drops of each solution were dropped in four directions of patients' eye immediately after applying anesthesia and before surgery. The incidence and severity of OCR during the stages of muscle release and incision (cutting), hemodynamic changes, the required time for OCR recovery and atropine dose were assessed.
Results:
OCR was more seen in release phase compared to cutting phase. There were no significant differences between two group regarding the incidence and severity of OCR in the release phase (p > 0.05), but the incidence and severity of OCR in the cutting phase was more in group E than group T (p = 0.02, for both). The duration of OCR improvement (p-value = 0.74) and Atropine consumption (p-value = 0.92) did not differ between the groups.
Conclusion:
Tetracaine eye drop only reduces the incidence and severity of OCR during the incision stage of strabismus surgery.
Related Concept Videos
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
Reflex Activity
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
Somatic Spinal Reflexes
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Oxidation-Reduction Reactions
Excess Pressure Inside a Drop and a Bubble
Block Diagram Reduction
The first step in this process is the identification and relocation of a branch point. A branch point, where a...

