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Updated: Jan 28, 2026

Extraction of High Molecular Weight DNA from Microbial Mats
Published on: July 7, 2011
Mini-review: Targeted radiopharmaceuticals incorporating reversible, low molecular weight albumin binders
Marie Brandt1, Jens Cardinale1, Carolina Giammei2
1Ludwig Boltzmann Institute Applied Diagnostics, General Hospital of Vienna, Vienna, Austria; Department of Biomedical Imaging and Image Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
Abstract:
The combination of low molecular weight, reversible human serum albumin (HSA) binders with targeted radiopharmaceuticals in dual-targeted radioconjugates holds great promise, in particular for endoradiotherapy. Attachment of HSA-binders to radiopharmaceuticals extends their blood circulation time and results in an enhanced tumour uptake as well as often in an improved pharmacokinetic profile. In this mini-review, an overview of currently pursued approaches of this novel strategy is provided.
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