Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

5.8K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.8K
Band Theory02:35

Band Theory

17.2K
When two or more atoms come together to form a molecule, their atomic orbitals combine and molecular orbitals of distinct energies result. In a solid, there are a large number of atoms, and therefore a large number of atomic orbitals that may be combined into molecular orbitals. These groups of molecular orbitals are so closely placed together to form continuous regions of energies, known as the bands.
The energy difference between these bands is known as the band gap.
Conductor, Semiconductor,...
17.2K
Distribution of Stresses in a Narrow Rectangular Beam01:11

Distribution of Stresses in a Narrow Rectangular Beam

522
In studying beam stress distribution, examining an elemental section is essential. To determine the average shearing stress on this face, the calculated shear is divided by the surface area. Importantly, shearing stresses on the beam's transverse and horizontal planes mirror each other, indicating a consistent stress distribution along the upper region of the beam. Notably, shearing stresses are absent at the beam's upper and lower surfaces due to the absence of applied forces in these...
522
Energy Bands in Solids01:01

Energy Bands in Solids

1.9K
Isolated atoms have discrete energy levels that are well described by the Bohr model. And, it quantifies the energy of an electron in a hydrogen atom as En. Higher quantum numbers 'n' yield less negative, closer electron energy levels.
 Band Formation:
When atoms are brought close together, as in a solid, these discrete energy levels begin to split due to the overlap of electron orbitals from adjacent atoms. This split occurs because of the Pauli exclusion principle, which states...
1.9K
Coping Strategies: Problem Focused01:27

Coping Strategies: Problem Focused

487
Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...
487
Light Acquisition02:16

Light Acquisition

9.6K
In order to produce glucose, plants need to capture sufficient light energy. Many modern plants have evolved leaves specialized for light acquisition. Leaves can be only millimeters in width or tens of meters wide, depending on the environment. Due to competition for sunlight, evolution has driven the evolution of increasingly larger leaves and taller plants, to avoid shading by their neighbors with contaminant elaboration of root architecture and mechanisms to transport water and nutrients.
9.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Ex vivo</i> localization of wireless implantable microdevice using high-resolution 3D imaging techniques.

Frontiers in bioengineering and biotechnology·2026
Same author

Towards a Nitinol-Based Microfabricated Approach to Repair Long-Gap Esophageal Atresia.

Micromachines·2026
Same author

Quality of life after preoperative home-based exercise training in patients with lung cancer: a secondary analysis.

Journal of thoracic disease·2026
Same author

Feasibility and Acceptability of an eHealth-Based Physical Activity Coaching Intervention During Pulmonary Rehabilitation for People With Chronic Obstructive Pulmonary Disease: Mixed Methods Study.

JMIR formative research·2026
Same author

Endocannabinoid modulation of a reciprocal fronto-coerulear connection in contextual discrimination.

Cell reports·2026
Same author

Post-stroke upper limb rehabilitation: clinical practices, compensatory movements, assessment, and trends.

Progress in biomedical engineering (Bristol, England)·2025

Related Experiment Video

Updated: Jan 28, 2026

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
08:58

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

16.6K

PDMS Microlenses for Focusing Light in Narrow Band Imaging Diagnostics.

Adriana C Costa1,2, Sara Pimenta3, João F Ribeiro4

  • 1Chongqing Key Laboratory of Colleges and Universities on Micro-Nano Systems Technology and Smart Transducing, Chongqing Engineering Laboratory for Detection, Institute of Applied Micro-Nano Science and Technology-IAMNST, Control and Integrated System, National Research Base of Intelligent Manufacturing Service, Chongqing Technology and Business University, Nan'an District,Chongqing 400067, China. adriana.c.costa@dei.uminho.pt.

Sensors (Basel, Switzerland)
|March 6, 2019
PubMed
Summary

Researchers enhanced illumination intensity for Narrow Band Imaging (NBI) in minimally invasive devices. This improvement in endoscopic capsules can boost diagnostic accuracy for early gastric lesion detection.

Keywords:
Narrow Band Imaging (NBI)Polydimethylsiloxane (PDMS) µ-lensminimally invasive medical devices

More Related Videos

Stretching Micropatterned Cells on a PDMS Membrane
09:41

Stretching Micropatterned Cells on a PDMS Membrane

Published on: January 22, 2014

15.9K
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

9.2K

Related Experiment Videos

Last Updated: Jan 28, 2026

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device
08:58

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

16.6K
Stretching Micropatterned Cells on a PDMS Membrane
09:41

Stretching Micropatterned Cells on a PDMS Membrane

Published on: January 22, 2014

15.9K
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

9.2K

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Optical Devices

Background:

  • Narrow Band Imaging (NBI) enhances gastrointestinal tract diagnostics by utilizing specific light wavelengths for mucosal layer penetration.
  • Optimizing light intensity is crucial for minimally invasive devices like endoscopic capsules to improve diagnostic accuracy.
  • Current endoscopic capsules use RGB LEDs, but light intensity can be a limiting factor for detailed imaging.

Purpose of the Study:

  • To develop a method for increasing illumination intensity in NBI for minimally invasive medical devices, specifically endoscopic capsules.
  • To enhance the diagnostic capabilities of NBI without increasing device size or power consumption.
  • To improve the resolution of NBI in endoscopic capsules for better early gastric lesion diagnosis.

Main Methods:

  • Designed a polydimethylsiloxane (PDMS) micro-lens (µ-lens) to maximize light intensity at the target area.
  • Fabricated the PDMS µ-lens using a cost-effective hanging droplet method.
  • Integrated the µ-lens with RGB LEDs in a prototype endoscopic capsule.

Main Results:

  • Achieved increased illumination intensity by a factor of 1.21 for blue and green LEDs.
  • Observed an increased illumination intensity by a factor of 1.18 for red LEDs.
  • Demonstrated enhanced light delivery without altering device size or power requirements.

Conclusions:

  • The developed PDMS µ-lens effectively increases NBI illumination intensity in endoscopic capsules.
  • This enhancement holds potential for improving the resolution of NBI, aiding in early detection of gastric pathologies.
  • The low-cost fabrication method makes this approach suitable for widespread application in minimally invasive diagnostics.