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Related Experiment Videos

Sensorineural hearing loss associated with systemic lupus erythematosus.

C A Bowman, F H Linthicum, R A Nelson

    Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
    |February 1, 1986
    PubMed
    Summary

    Systemic lupus erythematosus (SLE) may be linked to hearing loss. A study found 8% of SLE patients had previously undetected hearing issues, unrelated to common factors.

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    Area of Science:

    • Rheumatology
    • Otolaryngology
    • Audiology

    Background:

    • Clinical observations suggested a link between hearing loss and systemic lupus erythematosus (SLE).
    • Hearing impairment is a potential, often overlooked, comorbidity in autoimmune diseases.
    • The audiological impact of SLE requires further prospective investigation.

    Purpose of the Study:

    • To prospectively assess the incidence of previously undetected hearing loss in patients hospitalized with SLE exacerbation.
    • To investigate potential correlations between hearing loss and clinical/laboratory parameters in SLE patients.
    • To raise awareness among otolaryngologists and SLE physicians about this potential association.

    Main Methods:

    • Prospective audiological evaluation of 30 patients hospitalized for SLE exacerbation.

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  • Assessment of hearing loss in patients, with 29 receiving immunosuppressive therapy.
  • Correlation analysis of hearing loss with age, sex, disease activity, organ involvement, and lab abnormalities.

    • Main Results:

    • An 8% incidence of substantial, previously undetected hearing loss was identified in the SLE patient cohort.
    • No significant correlation was found between hearing loss and age, sex, disease activity, organ system involvement, or laboratory abnormalities.
    • The cause of hearing loss in these patients remained undetermined within the study's scope.

    Conclusions:

    • A notable incidence of previously undetected hearing loss exists in patients with SLE.
    • Hearing loss in SLE patients may not be directly correlated with disease activity or common clinical factors.
    • Physicians should consider hearing loss in the differential diagnosis of unexplained auditory symptoms in SLE patients and recommend otologic evaluation.