Gut Microbiome, Probiotics and Bone: An Updated Mini Review

Area of Science:

• Microbiology
• Immunology
• Endocrinology
• Bone Biology

Background:

• The gut microbiome is increasingly recognized as a significant factor influencing host physiology.
• It impacts the gastrointestinal tract, immune system, and endocrine functions.
• Emerging research suggests a connection between gut microbiota and bone metabolism.

Purpose of the Study:

• To review the current understanding of the gut microbiome's role in bone health.
• To explore the potential of probiotics in managing bone health.
• To summarize recent findings on the gut-bone axis.

Main Methods:

• Literature search of PubMed and Scopus databases.
• Review of recent scientific articles on gut microbiome, probiotics, and bone.
• Synthesis of available data on the gut-bone axis.

Main Results:

• The gut microbiome affects multiple host systems, including potentially bone metabolism.
• Probiotics demonstrate a positive influence on bone health management.
• Evidence suggests the gut microbiota plays a role in regulating bone formation and destruction.

Conclusions:

• The gut microbiome is a critical regulator of host health, with implications for bone.
• Probiotics represent a promising avenue for supporting healthy bone.
• Further research is warranted to fully elucidate the gut-bone axis and therapeutic potential of probiotics.