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Updated: Jan 28, 2026

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
Published on: December 7, 2013
Acute penetrating atherosclerotic ulcer of the ascending aorta
Manuel R Cervetti1, Mariano Camporrotondo1, Paz Ricapito1
1Cardiac Surgery Department, Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina.
Insights
A penetrating atherosclerotic ulcer (PAU) is a serious aortic condition. This case highlights successful surgical repair using a bovine pericardial patch for a calcified aortic root.
Area of Science:
- Cardiovascular Surgery
- Vascular Medicine
- Diagnostic Imaging
Background:
- Penetrating atherosclerotic ulcer (PAU) is a degenerative aortic disease.
- PAU can present with chest pain, mimicking acute coronary syndromes.
- Early diagnosis and intervention are crucial for managing PAU.
Observation:
- A 67-year-old male presented with persistent chest pain and hypertension.
- Diagnostic workup including ECG and cardiac enzymes ruled out acute coronary syndrome.
- Aortography and CT scan revealed an irregular aortic wall and the characteristic shape of a penetrating ulcer.
Findings:
- Intraoperative examination confirmed the diagnosis of penetrating atherosclerotic ulcer (PAU).
- Surgical repair involved coronary artery bypass graft and bovine pericardial patch repair of the PAU.
- The aortic root was heavily calcified, making the bovine pericardial patch a suitable and hemostatic choice.
Implications:
- This case demonstrates the successful surgical management of a complex PAU.
- Bovine pericardial patch repair is an effective option for PAU in the context of a calcified aortic root.
- Accurate imaging and timely surgical intervention are vital for favorable outcomes in PAU patients.
Abstract:
A 67-year-old man presented with chest pain. Clinical examination revealed hypertension (160/90 mm Hg). Electrocardiogram indicated no acute coronary syndrome and cardiac enzymes were normal. Catheterization was performed owing to the patient's continuing chest pain and ascending aortogram revealed irregular aortic wall. A computed tomography image showed the shape of penetrating ulcer. The patient was taken to the operating room and intraoperative examination confirmed the diagnosis of penetrating atherosclerotic ulcer (PAU). Coronary artery bypass graft and bovine pericardial patch repair of PAU was performed. A bovine pericardial patch was done as aortic root was heavily calcified and was easy to handle and more hemostatic.
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