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Antibioprophylaxis in surgery and interventional medicine (adult patients). Update 2017
C Martin1, C Auboyer2, M Boisson3
1Anaesthesia and intensive Care, North university hospital, 13015 Marseille, France.
Abstract:
Infection is a risk for any intervention. In surgery, for example, pathogenic bacteria are found in more than 90% of operative wounds during closure. This exists whatever the surgical technique and whatever the environment (the laminar flow does not entirely eliminate this risk). These bacteria are few in number but can proliferate. They find in the operative wound a favourable environment (haematoma, ischaemia, modification of oxido-reduction potential...) and the intervention induces anomalies of the immune defences. In the case of the installation of foreign material, the risk is increased. The objective of antibiotic prophylaxis (ABP) is to prevent bacterial growth in order to reduce the risk of infection at the site of the intervention. The preoperative consultation represents a privileged moment to decide on the prescription of a ABP. It is possible to define the type of intervention planned, the associated risk of infection (and therefore the necessity or not of ABP), the time of prescription before surgery and any allergic antecedents which may modify the choice of the selected antibiotic molecule.
Insights
Antibiotic prophylaxis (ABP) prevents bacterial growth, reducing surgical site infections. Preoperative consultations are key to determining the need for ABP, timing, and appropriate antibiotic choice based on patient allergies and infection risk.
Area of Science:
- Surgical site infection prevention
- Antimicrobial stewardship
Background:
- Surgical wounds frequently harbor pathogenic bacteria, increasing infection risk.
- Foreign material implantation further elevates infection risk.
- Surgical interventions can compromise local immune defenses.
Purpose of the Study:
- To outline the role of antibiotic prophylaxis (ABP) in preventing surgical site infections.
- To highlight the preoperative consultation as a critical juncture for ABP decision-making.
Main Methods:
- Review of factors influencing surgical site infection risk.
- Identification of key considerations for antibiotic prophylaxis prescription.
Main Results:
- Pathogenic bacteria are present in over 90% of operative wounds.
- ABP aims to inhibit bacterial proliferation in the operative wound.
- Preoperative assessment allows for tailored ABP strategies.
Conclusions:
- Antibiotic prophylaxis is crucial for mitigating infection risk in surgical interventions.
- Personalized preoperative evaluation ensures optimal antibiotic selection and administration timing.
- Effective ABP management reduces the incidence of surgical site infections.
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