Related Experiment Video

Updated: Sep 1, 2026

Mouse Mammary Epithelial Cells form Mammospheres During Lactogenic Differentiation
04:51

Mouse Mammary Epithelial Cells form Mammospheres During Lactogenic Differentiation

Published on: October 6, 2009

Mammillo-hypophyseal duplication (diplo-mammillo-hypophysis)

F Tagliavini, G Pilleri

    Acta Neuropathologica
    |January 1, 1986
    PubMed

    A first-time description is given of a unique combination of congenital deformities encountered in a female infant born in the 35th week of gestation and surviving for minutes only. The principal malformations comprised duplicity of the hypophysis cerebri and mammillary bodies, olfactory aplasia, agenesis of corpus callosum, Dandy-Walker syndrome, thoracolumbo-sacral rachischisis and hydromyelia, associated with palato-gnatho-cheilo-schisis, defects in the pericardium and cardiac interventricular septum and gross maldevelopment of the diaphragm. Of these cerebral anomalies, we have chosen to concentrate on the condition which we denominate "diplo-mammillo-hypophysis" (mammillo-hypophyseal duplication) as the object of this study. On grounds of embryonal development it is considered to have come about during the first half of the 2nd month of gestation. The likely genesis of the pathologic findings is discussed.

    More Related Videos

    Evaluation of Mammary Gland Development and Function in Mouse Models08:51

    Evaluation of Mammary Gland Development and Function in Mouse Models

    Published on: July 21, 2011

    Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland11:13

    Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland

    Published on: December 1, 2015

    Related Concept Videos

    Oogenesis02:07

    Oogenesis

    In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
    Cloning of Dolly the Sheep01:08

    Cloning of Dolly the Sheep

    The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual,  the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter telomeres than other...
    The Pituitary Gland01:17

    The Pituitary Gland

    The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
    The Parathyroid Glands00:59

    The Parathyroid Glands

    The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
    Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
    Oogenesis01:22

    Oogenesis

    Oogenesis,  the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
    Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
    The Mammary Glands01:12

    The Mammary Glands

    The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
    Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...