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Generation and Isolation of Cell Cycle-arrested Cells with Complex Karyotypes
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Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins

Alice McSweeney1, Colin Davies2, Vernon K Ward3

  • 1Department of Microbiology & Immunology, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand. alice.mcsweeney@postgrad.otago.ac.nz.

Viruses
|March 7, 2019
PubMed
Summary

Murine norovirus (MNV) viral protein genome-linked (VPg) induces a cell cycle arrest for replication. This G0/G1 arrest is conserved across norovirus genogroups and involves the N-terminal region of VPg.

Keywords:
CaliciviridaeG0/G1MNVVPgcell cyclenorovirus

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