Toward a Reconceptualization of Stem Cells from Cellular Plasticity
Related Experiment Video
Updated: Jan 28, 2026

Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips
Published on: May 3, 2019
Tao Liu1, Li Chen2, Zhongjian Zhao3
1Department of Infectious Diseases, Navy No.971 Hospital (formerly known as No.401 Hospital) of Chinese PLA, Qingdao, China.
Abstract:
The slow progress in clinical applications of stem cells and the bewildering mechanisms involved have puzzled many researchers. Recently, the increasing evidences have indicated that cells have superior plasticity in vivo or in vitro, spontaneously or under extrinsic specific inducers. The concept of stem cells may be challenged, or even replaced by the concept of cell plasticity when cell reprogramming technology is progressing rapidly. The characteristics of stem cells are manifestations of cellular plasticity. Incorrect understanding of the concept of stem cells hinders the clinical application of so-called stem cells. Understanding cellular plasticity is important for understanding and treating disease. The above issues will be discussed in detail to prove the reconceptualization of stem cells from cellular plasticity.
Related Concept Videos
Plasticizers
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
Plasticity
Adult Stem Cells
Embryonic Stem Cells
Plastic Behavior
Plastic Deformations

