Related Experiment Video
Updated: Jan 28, 2026
10:41
Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools
Published on: December 16, 2015
9.3K
Long Non-coding RNAs Coordinate Developmental Transitions and Other Key Biological Processes in Grapevine
Garima Bhatia1, Shailesh Sharma2, Santosh Kumar Upadhyay3
1Department of Biotechnology, Panjab University, 160014, Chandigarh, India.
Scientific Reports
|March 7, 2019
Summary
This study identified 56,441 long non-coding RNAs (lncRNAs) in grapevine, revealing their crucial roles in regulating development and metabolic pathways. These findings enhance our understanding of gene regulation in this economically important fruit crop.
Area of Science:
- Plant molecular biology
- Genomics
- Transcriptomics
Background:
- Long non-coding RNAs (lncRNAs) are key regulatory molecules in eukaryotes.
- Understanding lncRNA roles is crucial for crop improvement.
Purpose of the Study:
- To identify and characterize lncRNAs in grapevine (Vitis vinifera).
- To investigate the spatiotemporal regulation and functions of grapevine lncRNAs.
Main Methods:
- Computational analysis of RNA-seq data from 10 developmental stages and tissues.
- Differential expression analysis, co-expression analysis, and pathway enrichment analysis.
- Identification of lncRNA interactions with microRNAs (miRNAs), transcription factors (TFs), and organellar genes.
Main Results:
- 56,441 grapevine lncRNAs were identified and characterized.
- lncRNAs exhibit tissue- and developmental stage-specific expression, indicating spatiotemporal regulation.
- lncRNAs are involved in regulating developmental transitions, metabolic pathways, and interact with miRNAs, TFs, and organellar genes.
Conclusions:
- Grapevine lncRNAs are integral to coordinating complex biological functions.
- This study provides a foundation for future research into lncRNA-mediated regulatory mechanisms in grapevine development and metabolism.
More Related Videos
Related Concept Videos
02:39lncRNA - Long Non-coding RNAs
9.9K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.9K
02:39lncRNA - Long Non-coding RNAs
3.6K
3.6K
02:57Coordination Number and Geometry
19.0K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
19.0K
02:30siRNA - Small Interfering RNAs
18.6K
Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
18.6K
02:57piRNA - Piwi-interacting RNAs
7.6K
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
7.6K
01:29Coordination of Gene Expression Processes in Bacteria
636
The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
636