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EBV Infection Unmasking a Choledochal Cyst in an Infant

Hassan El Khatib1, Batoul Kawtharany1, Diyaa Mohammad2

  • 1Department of Pediatrics, Makassed General Hospital, Beirut, Lebanon.

Case Reports in Pediatrics
|March 7, 2019
PubMed

Insights

Epstein-Barr virus (EBV) infection can cause liver issues in children. This case highlights a rare instance of obstructive jaundice in an infant, revealing a choledochal cyst.

Area of Science:

  • Pediatric Hepatology
  • Viral Infections
  • Gastroenterology

Background:

  • Epstein-Barr virus (EBV) commonly causes hepatic involvement in children, typically mild transaminase elevation.
  • Cholestatic patterns with elevated gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) are observed, but jaundice is rare in pediatric cases.

Observation:

  • An 8-month-old female presented with obstructive jaundice two weeks post-EBV infection.
  • Radiological findings indicated a Type IVa choledochal cyst with common bile duct stone formation.

Findings:

  • The patient's obstructive jaundice was attributed to a choledochal cyst, not solely the EBV infection.
  • This case underscores that severe presentations warrant investigation beyond the primary viral illness.

Implications:

  • Close monitoring of liver function tests in pediatric EBV infections is crucial.
  • Prompt investigation for underlying conditions like choledochal malformations is essential in cases of clinical exacerbation or persistent liver dysfunction.

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