Related Experiment Video
Updated: Jan 28, 2026

Comparative in vivo Study of gp96 Adjuvanticity in the Frog Xenopus laevis
Published on: September 16, 2010
Microbiology of smegma: Prospective comparative control study
Jae Min Chung1,2, Chang Soo Park1, Sang Don Lee1,2
1Department of Urology, Pusan National University School of Medicine, Yangsan, Korea.
Smegma in asymptomatic boys frequently contains various bacteria, including multi-drug resistant strains. The presence of smegma influences the types of bacteria found on the glans.
Area of Science:
- Microbiology
- Pediatric Urology
Background:
- Smegma, a natural secretion, accumulates in the subpreputial space.
- Understanding the microbial composition of smegma is crucial for pediatric hygiene and health.
Purpose of the Study:
- To identify common bacteria in the smegma of asymptomatic boys.
- To compare bacterial presence in the subpreputial space with and without smegma.
Main Methods:
- Prospective study of 40 boys undergoing penoplasty.
- Aseptic swabs collected from glans and smegma.
- Microscopy, culture, and sensitivity testing performed on samples.
Main Results:
- Thirty-one bacterial species were isolated, with a near-equal distribution of gram-positive and gram-negative bacteria.
- Escherichia coli, Enterococcus faecalis, and Enterococcus avium were the most common isolates.
- A significant proportion (61.3%) of isolates were multi-drug resistant.
Conclusions:
- Subpreputial smegma in children is a reservoir for various uropathogens.
- Bacterial colonization patterns differ based on the presence or absence of smegma.
Related Concept Videos
History of Microbiology
Three-Dimensional Microscopy in Microbiology
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Two-Dimensional Microscopy in Microbiology
Key Techniques in Microbiology
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...

