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5-Endo-dig cyclizations in organic syntheses
Muhammad Aamir Sajid1, Zulfiqar Ali Khan2, Sohail Anjum Shahzad3
1Department of Chemistry, Faculty of Physical Sciences, Government College University, Faisalabad, 38000, Pakistan.
Abstract:
The favorability of ring closure reactions as per Baldwin rules has gained immense importance recently. This is evident from the current literature such as research articles, reviews, and books that have been published in this area. This review covers the recent applications of 5-endo-dig cyclization in organic synthesis focusing in the last two decades. A variety of 5-membered heterocycles as well as carbocycles could be synthesized via 5-endo-dig cyclization reactions. The important applications of 5-endo-dig cyclization in organic synthesis covering different aspects have been summarized in this review.
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