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Updated: Jan 28, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Published on: November 3, 2010

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Allele-specific expression variation at different ploidy levels in Squalius alburnoides

Isa Matos1,2, Miguel P Machado1,2,3, Manfred Schartl4,5,6

  • 1Faculdade de Ciências, cE3c- Centro de Ecologia, Evolução e Alterações Ambientais, Departamento de Biologia Animal, Universidade de Lisboa Campo Grande, 1749-016, Lisboa, Portugal.

Scientific Reports
|March 8, 2019
PubMed
Summary

Allopolyploid vertebrates like the Iberian fish Squalius alburnoides exhibit homoeolog expression bias, where parental gene copies are expressed unevenly. This study reveals genome-wide bias and allelic silencing, crucial for stable polyploid genomes.

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