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Updated: Jan 28, 2026
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Facilitating Drug Discovery: An Automated High-content Inflammation Assay in Zebrafish
Published on: July 16, 2012
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Publisher Correction: Death by inflammation: drug makers chase the master controller
1, Dublin, Ireland. l.melton@nature.com.
Nature Biotechnology
|March 8, 2019
Summary
A correction has been issued regarding a GlaxoSmithKline compound previously misidentified as a RIPK1 inhibitor. The compound GSK2983559 is actually a RIPK2 inhibitor and has been removed from relevant study data.
Area of Science:
- Pharmacology
- Drug Discovery
- Inflammatory Diseases
Background:
- A previous publication incorrectly listed GSK298559 as a RIPK1 inhibitor.
- This compound was noted in phase 1 trials for inflammatory bowel disease.
Purpose of the Study:
- To correct a factual error in the published article.
- To accurately represent the target and classification of the GlaxoSmithKline compound.
Main Methods:
- Review of compound designation and target.
- Correction of erroneous data in published tables.
Main Results:
- The compound GSK298559 was correctly identified as a RIPK2 inhibitor, not a RIPK1 inhibitor.
- The incorrect table entry has been removed from the article.
Conclusions:
- Accurate reporting of drug targets is crucial for scientific integrity.
- This correction ensures the precise information regarding RIPK2 inhibitors in inflammatory disease research.
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