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Related Concept Videos

Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

5.1K
Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
5.1K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

8.6K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
8.6K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

2.8K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
2.8K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

2.7K
Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.7K
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

14.9K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
14.9K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.1K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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Related Experiment Video

Updated: Jan 28, 2026

Kinetic Measurement and Real Time Visualization of Somatic Reprogramming
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Kinetic Measurement and Real Time Visualization of Somatic Reprogramming

Published on: July 30, 2016

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[Somatization].

Rino Scuccato1

  • 1Neurologo libero professionista, Vicenza.

Recenti Progressi in Medicina
|March 8, 2019
PubMed
Summary

Neurological functional disorders, like migraine, present diagnostic challenges. Advances in neuroscience suggest these are manifestations of cerebral suffering, influenced by patient history and culture.

Area of Science:

  • Neurology
  • Neuroscience
  • Psychiatry

Background:

  • Functional neurological disorders present significant diagnostic and terminological challenges.
  • Conditions like migraine and narcolepsy lack demonstrable lesions but have recognized status.
  • Some functional disorders are misattributed to psychic conflicts, risking overlooked organic pathologies.

Purpose of the Study:

  • To address the terminological and diagnostic issues surrounding functional neurological disorders.
  • To explore the neuroscientific basis of these conditions.
  • To integrate cultural and existential factors into understanding neurological disease presentation.

Main Methods:

  • Review of current neurological and psychiatric nosography.
  • Analysis of the impact of neuroscience advancements on understanding brain function.

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De Novo Generation of Somatic Stem Cells by YAP/TAZ
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De Novo Generation of Somatic Stem Cells by YAP/TAZ

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In Vivo Calcium Imaging of Dorsal Root Ganglia Neurons' Response to Somatic and Visceral Stimuli
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In Vivo Calcium Imaging of Dorsal Root Ganglia Neurons' Response to Somatic and Visceral Stimuli

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Related Experiment Videos

Last Updated: Jan 28, 2026

Kinetic Measurement and Real Time Visualization of Somatic Reprogramming
08:56

Kinetic Measurement and Real Time Visualization of Somatic Reprogramming

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De Novo Generation of Somatic Stem Cells by YAP/TAZ
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De Novo Generation of Somatic Stem Cells by YAP/TAZ

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In Vivo Calcium Imaging of Dorsal Root Ganglia Neurons' Response to Somatic and Visceral Stimuli
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  • Consideration of patient-reported experiences and cultural influences on symptom perception.

    • Main Results:

    • Functional disorders represent a spectrum of cerebral suffering, not solely psychogenic.
    • The distinction between 'functional' and 'lesional' is becoming blurred with technological progress.
    • Patient cultural background significantly modulates the clinical expression of neurological conditions.

    Conclusions:

    • All functional neurological disorders should be viewed as expressions of underlying cerebral dysfunction.
    • Neuroscience supports a unified view of neurological and psychiatric conditions originating in the brain.
    • An integrated approach considering biological, psychological, and social factors is crucial for accurate diagnosis and treatment.