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Updated: Jan 28, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
Published on: March 2, 2020
A Cd-MOF as a fluorescent probe for highly selective, sensitive and stable detection of antibiotics in water
Pengcheng Xing1, Di Wu, Jingshuai Chen
1Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybird Functionalized Materials, College of Chemistry and Chemical Engineering, Anhui University, Hefei 230039, PR China. niuhelin@ahu.edu.cn.
Abstract:
Recently, the pollution and damage caused by antibiotics in water have aroused serious concerns. In this situation, it is extremely important to develop a highly effective approach to detect antibiotics in water. In this contribution, we built a Cd-MOF material with stable fluorescence properties, using bbi = 1,4-bis(2-methyl-imidazol-1-yl)butane and H2L = 1,2-phenylenediacetic acid as organic ligands and Cd(NO3)2·4H2O as the metal node. The highly selective response of this MOF probe to ceftriaxone sodium (an antibiotic) can reach up to the ppb level in water, along with a fast response time, acid and alkali resistance, and anti-interference ability.
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