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Updated: Jan 28, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
Modelling the dynamics of direct and pathogens-induced dysentery diarrhoea epidemic with controls
Hailay Weldegiorgis Berhe1, Oluwole Daniel Makinde2, David Mwangi Theuri3
1Pan African University Institute of Basic Sciences Technology and Innovation, Nairobi, Kenya.
Abstract:
In this paper, the dysentery dynamics model with controls is theoretically investigated using the stability theory of differential equations. The system is considered as SIRSB deterministic compartmental model with treatment and sanitation. A threshold number is obtained such that indicates the possibility of dysentery eradication in the community while represents uniform persistence of the disease. The Lyapunov-LaSalle method is used to prove the global stability of the disease-free equilibrium. Moreover, the geometric approach method is used to obtain the sufficient condition for the global stability of the unique endemic equilibrium for . Numerical simulation is performed to justify the analytical results. Graphical results are presented and discussed quantitatively. It is found out that the aggravation of the disease can be decreased by using the constant controls treatment and sanitation.
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