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Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking
Published on: August 6, 2013
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Secondhand Smoke and CKD
Jong Hyun Jhee1,2, Young Su Joo1, Youn Kyung Kee3
1Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
Summary
Secondhand smoke exposure increases the risk of chronic kidney disease (CKD) in never-smokers. This study found a higher prevalence and incidence of CKD among non-smokers exposed to secondhand smoke.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Background:
- Active smoking is a known risk factor for various diseases, including chronic kidney disease (CKD).
- The impact of secondhand smoke exposure on CKD development among never-smokers remains less understood.
- Investigating this association is crucial for public health initiatives and preventive strategies.
Purpose of the Study:
- To examine the association between secondhand smoke exposure and the risk of CKD development in never-smokers.
- To determine if varying frequencies of secondhand smoke exposure correlate with different CKD risks.
- To provide evidence on the detrimental effects of environmental tobacco smoke on kidney health.
Main Methods:
- Analysis of 131,196 never-smokers from the Korean Genome and Epidemiology Study (2001-2014).
- Participants categorized by secondhand smoke exposure frequency: none, <3 days/week, and ≥3 days/week.
- Cross-sectional analysis for prevalent CKD and longitudinal analysis for incident CKD development.
Main Results:
- Higher odds of prevalent CKD were observed in individuals exposed to secondhand smoke (<3 days/week: OR 1.72; ≥3 days/week: OR 1.44).
- Longitudinal analysis showed an increased risk of incident CKD in those exposed to secondhand smoke (≥3 days/week: HR 1.66).
- These associations remained significant after adjusting for potential confounders.
Conclusions:
- Secondhand smoke exposure is significantly associated with both the prevalence and development of chronic kidney disease in never-smokers.
- Even moderate exposure to secondhand smoke poses a risk to kidney health.
- Reducing secondhand smoke exposure is recommended to prevent CKD.
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