A review of aortic disease research in Malaysia

Area of Science:

• Cardiovascular Research
• Public Health
• Medical Literature Review

Background:

• Aortic disease encompasses various conditions including aneurysms and acute aortic syndromes.
• Understanding the landscape of aortic disease research in Malaysia is crucial for advancing patient care.
• Previous research on aortic disease in Malaysia has not been comprehensively reviewed.

Purpose of the Study:

• To systematically review all research on aortic disease conducted in Malaysia between 2000 and 2016.
• To provide insights into the epidemiology, pathophysiology, and clinical management of aortic diseases in Malaysia.
• To identify limitations in current research and propose recommendations for future studies and clinical practice.

Main Methods:

• A comprehensive literature search was performed across multiple databases: PubMed, Scopus, MyJurnal, and the UKM Journal Repository.
• The search utilized specific Medical Subject Headings (MeSH) terms: "aortic", "aorta", and "Malaysia".
• A total of 213 papers were identified, with 60 selected for in-depth review based on relevance.

Main Results:

• The review analyzed 60 relevant papers, covering epidemiology, pathophysiology, clinical presentations, case reports, investigations, treatment, and outcomes of aortic disease in Malaysia.
• Key findings on the prevalence and characteristics of aortic diseases within the Malaysian population were summarized.
• The clinical relevance and implications of the reviewed studies were discussed.

Conclusions:

• The review offers a comprehensive overview of aortic disease research in Malaysia, detailing its pathophysiology, prevalence, and epidemiology.
• Current management strategies and treatment outcomes for aortic conditions in Malaysia were elucidated.
• Significant limitations in existing research were identified, leading to recommendations for future research directions and enhancements in clinical practice.