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Bone healing dynamics associated with 3 implants with different surfaces: histologic and histomorphometric analyses
Jungwon Lee1, Jung Min Yoo2, Heithem Ben Amara2
1Department of Periodontics, One-Stop Specialty Center, Seoul National University Dental Hospital, Seoul, Korea.
Journal of Periodontal & Implant Science
|March 9, 2019
Summary
Dental implant surface properties significantly impact bone healing and osseointegration. Hydroxyapatite-coated implants show enhanced osteoblast activity during remodeling, suggesting improved bone healing dynamics.
Area of Science:
- Biomaterials Science
- Dental Implantology
- Bone Regeneration
Background:
- Dental implant surface characteristics are crucial for osseointegration and long-term success.
- Different surface treatments aim to enhance bone-to-implant contact and accelerate healing.
Purpose of the Study:
- To compare bone healing and remodeling in dogs using three distinct dental implant surfaces.
- Evaluate sandblasting and large-grit acid etching (SLA), SLA with hydroxyapatite nanocoating (HA), and SLA stored in saline (SLActive).
Main Methods:
- Surgical placement of implants in canine premolar extraction sites.
- Histologic and histomorphometric analysis at 2, 4, and 12 weeks post-surgery.
- Quantification of bone loss, bone-to-implant contact, and bone area fraction.
Main Results:
- Significant differences in osteoid-to-implant contact, bone-to-implant contact, and bone area fraction were found among implant surfaces.
- Healing time influenced marginal bone loss and bone-to-implant contact parameters.
- An interaction effect between implant surface and healing time was observed for key osseointegration metrics.
Conclusions:
- Implant surface wettability enhances early osseointegration and bone healing dynamics.
- Hydroxyapatite-coated surfaces may promote greater osteoblast activation during the bone remodeling phase compared to hydrophobic surfaces.
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