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Related Concept Videos

Inertia Tensor01:24

Inertia Tensor

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The concept of the inertia tensor is employed to depict the mass distribution and rotational inertia of a solid or rigid object. This tensor is expressed through a three-by-three matrix. Each component within this matrix corresponds to varying moments of inertia about specific axes.
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Diffusion01:12

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Diffusion01:21

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Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Although gaseous molecules travel at tremendous speeds (hundreds of meters per second), they collide with other gaseous molecules and travel in many different directions before reaching the desired target. At room temperature, a gaseous molecule will experience billions of collisions per second. The mean free path is the average distance a molecule travels between collisions. The mean free path increases with decreasing pressure; in general, the mean free path for a gaseous molecule will be...
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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Diffusion tensor imaging of diabetic amyotrophy.

Rocco Hlis1, Feng Poh1,2, Yin Xi1

  • 1UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9178, USA.

Skeletal Radiology
|March 9, 2019
PubMed
Summary
This summary is machine-generated.

Magnetic resonance neurography with diffusion tensor imaging can identify nerve damage in diabetic amyotrophy (DA). Increased ADC values correlated with higher HbA1c, suggesting MRN with DTI as a diagnostic tool for suspected DA.

Keywords:
Diabetic amyotrophyDiabetic neuropathiesDiffusion tensor imagingLumbosacral plexusMagnetic resonance imaging

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Diabetic amyotrophy (DA) is a debilitating condition affecting nerves.
  • Accurate diagnostic tools are crucial for timely intervention.

Purpose of the Study:

  • To characterize nerve abnormalities in DA patients using MRN with DTI.
  • To quantitatively assess nerve damage and its correlation with glycemic control.

Main Methods:

  • MRN with DTI was performed on 13 DA patients and 40 controls.
  • Qualitative and quantitative analyses of lumbosacral nerve roots and major nerves were conducted.
  • Statistical analyses included ANOVA, regression, and ICC for reliability.

Main Results:

  • DA patients showed significant nerve abnormalities compared to controls.
  • Reduced nerve signal, increased ADC, and lower FA values were observed in DA.
  • Higher ADC values correlated positively with HbA1c levels.

Conclusions:

  • MRN with DTI effectively identifies neuromuscular lesions in DA.
  • This technique serves as a valuable non-invasive diagnostic tool for suspected DA.
  • Correlation between ADC and HbA1c highlights the link between nerve damage and glycemic control.