Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Thyroid Gland

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

Functions of Thyroid Hormones

Functions of Thyroid Hormones

The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...

Synthesis and Regulation of Thyroid Hormones

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...

Co-activators and Co-repressors

Co-activators and Co-repressors

Gene transcription is regulated by the synergistic action of several proteins that form a complex at a gene regulatory site. This is observed in eukaryotes, where the regulation of gene expression is a complex process. Regulatory proteins in eukaryotes can broadly be classified into two types – regulators that bind directly to specific DNA sequences and co-regulators that associate with regulatory proteins but cannot directly bind to the DNA. These co-regulators are further divided into...

What are Proteins?

What are Proteins?

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Higher frequency of subclonal anti-EGFR resistance mutations in post-treatment samples from patients with colorectal cancer liver metastases following anti-EGFR-based conversion chemotherapy.

PloS one·2026

Same author

Comparing 24 h Urine and Spot Urine Calcium Measurements in Clinical Routine: Accuracy and Limitations.

Journal of clinical medicine·2026

Same author

Autoimmune encephalitis-associated epilepsy with glutamic acid decarboxylase autoantibodies and type 1 diabetes mellitus: A comprehensive systematic scoping review of a clinical syndrome.

Autoimmunity reviews·2026

Same author

Thyroid Cancer: Epidemiology, Diagnosis, and Treatment.

Deutsches Arzteblatt international·2026

Same author

Real-World Efficacy and Safety of Lenvatinib and Sorafenib in Thyroid Cancer: A Retrospective, Propensity-Score-Matched Study.

Thyroid : official journal of the American Thyroid Association·2026

Same author

Acute Changes in Liver and Spleen Stiffness Following Endoscopic Variceal Ligation in Advanced Liver Disease-A Pilot Study.

Journal of clinical medicine·2026

Search research articles

Related Experiment Video

Updated: Jan 28, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

[Thyroid Elastography].

Jörg Bojunga¹, Antonia Mondorf¹

¹Medizinische Klinik I, Schwerpunkt Endokrinologie, Diabetologie, Ernährungsmedizin, Universitätsklinikum Frankfurt.

Laryngo- Rhino- Otologie

|March 9, 2019

Summary

This summary is machine-generated.

Ultrasound elastography improves the assessment of thyroid nodules, offering a reproducible method to evaluate tissue consistency. This technique aids in differentiating benign from malignant nodules, potentially reducing unnecessary surgeries.

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment

Published on: March 1, 2024

Related Experiment Videos

Last Updated: Jan 28, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment

Published on: March 1, 2024

Area of Science:

Endocrinology
Medical Imaging
Oncology

Background:

Thyroid nodules are common, particularly in iodine-deficient areas.
Ultrasound detects nodules but struggles to differentiate benign from malignant types.
Fine-needle-aspiration biopsy (FNAB) is used for diagnosis, but many benign cases undergo surgery for confirmation.

Purpose of the Study:

To review current literature on ultrasound elastography techniques for thyroid nodules.
To evaluate elastography's effectiveness in differentiating benign and malignant thyroid nodules.
To discuss elastography's role in assessing diffuse thyroid diseases.

Main Methods:

Literature review of ultrasound elastography applications in thyroidology.
Analysis of studies reporting on nodule differentiation and diffuse thyroid disease evaluation.
Discussion of the advantages and limitations of elastography techniques.

Main Results:

Elastography provides a reproducible assessment of tissue consistency, overcoming the subjectivity of palpation.
Studies show promising results for elastography in improving the accuracy of thyroid nodule characterization.
Elastography also shows potential for evaluating diffuse thyroid conditions.

Conclusions:

Ultrasound elastography is a valuable tool for assessing thyroid nodule consistency.
It enhances diagnostic accuracy, potentially reducing unnecessary surgical interventions for benign nodules.
Further research is ongoing to fully establish elastography's role in thyroid diagnostics.