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Water/fat separation for distortion-free EPI with point spread function encoding.

Zhangxuan Hu1, Yishi Wang1, Zijing Dong1

  • 1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.

Magnetic Resonance in Medicine
|March 9, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a novel water/fat separation method for echo-planar imaging (EPI) using point spread function (PSF) encoding. The technique effectively suppresses fat signals in EPI, even with severe field inhomogeneity, without requiring additional scans.

Keywords:
chemical-shift artifactsdistortion-free imagingecho-planar imaging (EPI)point spread function (PSF)water/fat separation

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Area of Science:

  • Magnetic Resonance Imaging
  • Medical Physics
  • Image Processing

Background:

  • Chemical-shift artifacts in echo-planar imaging (EPI) pose a significant challenge, particularly in the presence of severe magnetic field inhomogeneity.
  • Effective artifact reduction is crucial for high-fidelity anatomical and functional imaging.

Purpose of the Study:

  • To develop a reliable water/fat separation technique for point spread function (PSF) encoded EPI (PSF-EPI).
  • To leverage intrinsic multiple echo-shifted images within PSF-EPI for artifact removal.
  • To achieve robust fat suppression in EPI without additional scanning sequences.

Main Methods:

  • Utilized chemical-shift encoding inherent in intermediate images of PSF-EPI.
  • Applied advanced water/fat separation algorithms to the PSF-EPI data.
  • Validated the method across T1-weighted, T2-weighted, and diffusion-weighted imaging in healthy volunteers.

Main Results:

  • Demonstrated successful in vivo water/fat separation using intrinsic PSF-EPI signals.
  • Showcased robust separation and fat residue removal across various imaging contrasts and regions.
  • Confirmed the method's efficacy without the need for extra acquisition time.

Conclusions:

  • The proposed PSF-EPI water/fat separation effectively suppresses fat signals, even under severe field inhomogeneity.
  • This technique is adaptable to multiple imaging contrasts, enhancing its versatility.
  • Distortion-free PSF-EPI offers potential for high-fidelity, efficient anatomical and functional imaging.