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Updated: Jan 28, 2026

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
Published on: December 10, 2021
Modulated Protein Delivery to Engineer Tissue Repair
Marian H Hettiaratchi1,2, Molly S Shoichet1,2,3,4
11Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada.
Impact Statement:
Achieving targeted protein delivery to injured tissues is a core focus of the field of tissue engineering and has enormous clinical potential. This article highlights significant advances made in biomaterial-based protein delivery strategies over the last 25 years and how they will influence research in the next 25 years. These advances will enable protein release rates to be tuned with increased flexibility to deliberately address the challenges of the dynamic injury environment and ultimately lead to better solutions for patients.
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