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Updated: Jan 28, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
First-row early transition metal complexes with a highly sterically demanding triisopropylphenyl amino triphenolate
Dae Young Bae1, Gyeong Su Park, Nakeun Ko
1Department of Chemistry, Pohang University of Science and Technology, 77 Cheongam-Ro, 37673 Pohang, Republic of Korea. eslee@postech.ac.kr.
Abstract:
Amino triphenolate ligands have been widely used for the synthesis of various transition metal complexes aiming at various applications such as ring-opening polymerization, olefin polymerization, and sulfoxidation. However, the introduction of highly sterically demanding aromatic substituents, such as triisopropylphenyl (TRIP), to the amino triphenolate ligand has not been previously reported probably due to the synthetic difficulty. In six-step reactions using commercial materials, a highly sterically demanding amino triphenolate ligand was successfully synthesized, and early transition metal complexes (Ti, V, Cr, Mn) supported by the ligand were also obtained and fully characterized. In addition, titanium and chromium complexes were further used for catalytic sulfoxidation, and polymerization of ethylene, respectively.
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