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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Preoperative Extracorporeal Membrane Oxygenation for Postinfarction Ventricular Septal Defect
Eilon Ram1, Alexander Kogan1, Boris Orlov1
11 Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ventricular septal defect (VSD) mortality is high. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) can serve as a crucial bridge to surgery for patients with postinfarction VSD experiencing cardiogenic shock.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Critical Care Medicine
Background:
- Ventricular septal defect (VSD) following myocardial infarction carries a high mortality rate.
- Despite advances, pharmaceutical, invasive cardiology, and surgical interventions have limitations.
- Urgent surgical repair is sometimes necessary for hemodynamically unstable patients.
Observation:
- Two patients with postinfarction VSD presented with cardiogenic shock and multiorgan failure.
- Optimal medical management did not stabilize their critical condition.
- Both patients required immediate intervention beyond standard care.
Findings:
- Venoarterial extracorporeal membrane oxygenation (VA-ECMO) was initiated for both patients.
- VA-ECMO provided hemodynamic support and end-organ perfusion.
- This mechanical circulatory support facilitated stabilization for subsequent surgical repair.
Implications:
- VA-ECMO can be a life-saving bridge therapy for severe postinfarction VSD.
- It allows for timely surgical intervention in critically ill patients.
- This approach may improve outcomes in complex VSD cases.
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