Ocular measurements of a swept-source biometer: Repeatability data and comparison with an optical low-coherence...

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Diagnostic Technology Evaluation

Background:

• Accurate ocular biometry is crucial for refractive surgery and intraocular lens (IOL) power calculation.
• Swept-source biometry offers potential advantages in speed and penetration depth compared to older technologies.
• Evaluating the performance of new diagnostic devices is essential for clinical adoption.

Purpose of the Study:

• To assess the repeatability of the Argos swept-source biometer for ocular measurements.
• To analyze astigmatism measurements using the Argos device.
• To compare the Argos biometer's data with measurements from an optical low-coherence interferometry (Aladdin) device.

Main Methods:

• One eye from 96 patients (50 phakic, 46 pseudophakic) was measured using both Argos and Aladdin devices.
• Three repeated measurements were performed with the Argos biometer.
• Biometric parameters, including astigmatism vector components, were analyzed; Bland-Altman plots were used for comparison.

Main Results:

• The Argos biometer demonstrated excellent repeatability for most parameters, with exceptions in astigmatism (both groups) and anterior chamber depth (pseudophakic group).
• Significant differences between Argos and Aladdin were found for corneal diameter in both phakic and pseudophakic eyes.
• Astigmatism measurements also differed significantly between devices in the phakic group.
• Intraclass correlation coefficients (ICC) were generally excellent for Argos, though moderate for anterior chamber depth in pseudophakic eyes.

Conclusions:

• The Argos swept-source biometer exhibits high repeatability for most ocular parameters, though astigmatism and ACD require careful consideration.
• Limited agreement exists between the Argos and Aladdin devices, particularly for astigmatism and corneal diameter.
• Further studies are needed to validate the clinical utility and agreement of swept-source biometry with existing methods.