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A novel range-verification method using ionoacoustic wave generated from spherical gold markers for particle-beam
Taisuke Takayanagi1,2, Tomoki Uesaka1, Masanori Kitaoka2
1Graduate School of Biomedical Science and Engineering, Hokkaido University, North-13 West-8, Kita-ku, Sapporo, Hokkaido, 060-8628, Japan.
Scientific Reports
|March 10, 2019
Summary
This study introduces a new proton beam range verification method using acoustic waves from metal markers. The marker
Area of Science:
- Medical Physics
- Acoustics
- Particle Therapy
Background:
- Proton beam therapy requires precise range verification for accurate dose delivery.
- Current range verification methods have limitations in real-time monitoring.
- Acoustic wave generation from material interactions is a developing field.
Purpose of the Study:
- To propose and validate a novel method for proton beam range verification using acoustic waves.
- To investigate the use of spherical metal markers as acoustic transmitters.
- To correlate acoustic wave properties with proton beam range.
Main Methods:
- 3-D simulations combining proton dose calculations and acoustic wave propagation modeling.
- Utilizing a 2.0 mm diameter spherical gold marker in water.
- Simulating a 60 MeV proton beam and analyzing generated acoustic waves.
Main Results:
- Observed high-frequency acoustic waves (1.62 MHz) generated from the gold marker.
- Demonstrated that acoustic wave amplitude correlates with the distance to the Bragg peak.
- Confirmed the marker acts as a resonant acoustic transmitter.
Conclusions:
- Proton beam range can be estimated by measuring acoustic wave amplitudes from a metal marker.
- This method offers a potential alternative for real-time range verification.
- A single, resonance-frequency-tuned detector could enable this measurement.
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