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Updated: Jan 28, 2026
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Basophil Activation Test for Allergy Diagnosis
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Experience in patch testing: A 6-year retrospective review from a single academic allergy practice
Britta K Sundquist1, Barbara Yang2, M Asghar Pasha1
1Division of Allergy and Immunology, Department of Medicine, Albany Medical College, Albany, NY.
Summary
Patch testing is crucial for diagnosing allergic contact dermatitis (ACD). Extended allergen panels significantly increase diagnostic sensitivity compared to limited tests like the T.R.U.E. Test.
Area of Science:
- Allergy and Immunology
- Dermatology
- Contact Dermatitis Research
Background:
- Patch testing is the gold standard for identifying allergens in allergic contact dermatitis (ACD).
- Limited data exists on patch testing outcomes within allergy practice settings.
Purpose of the Study:
- To analyze patch test findings in a large academic allergy practice.
- To compare the sensitivity of extended allergen panels versus limited series (T.R.U.E. Test).
Main Methods:
- Retrospective chart review of 585 patients over 6 years.
- Analysis of patch testing results, atopy history, dermatitis location, and referral sources.
Main Results:
- 63% of patients had positive patch tests; nickel sulfate was the most common allergen.
- Extended screening identified an additional 10.8% of positive cases missed by the T.R.U.E. Test.
- Extremities were the most common dermatitis site.
Conclusions:
- Patch testing is valuable for allergists in diagnosing ACD.
- Extended allergen panels enhance diagnostic sensitivity over limited series.
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