Related Experiment Video

Updated: Jan 28, 2026

Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

20.2K

Predictive value of interatrial block for atrial fibrillation in elderly subjects enrolled in the PREDICTOR study

Alessandro Boccanelli1, Gian Francesco Mureddu2, Giulia Cesaroni3

  • 1Casa di Cura Quisisana, Rome, Italy.

Journal of Electrocardiology
|March 10, 2019
PubMed

Insights

Interatrial block (IAB) is linked to a higher risk of developing atrial fibrillation (AF). This electrical condition appears to predict AF independently of structural heart changes, particularly in normal-weight individuals.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Preventive Medicine

Background:

  • Atrial fibrillation (AF) is a common arrhythmia with significant morbidity.
  • Interatrial block (IAB) is an electrocardiographic finding reflecting delayed conduction between the atria.
  • The relationship between IAB and the future risk of AF, independent of structural heart disease, requires further elucidation.

Purpose of the Study:

  • To investigate the association between the presence of interatrial block (IAB) and the subsequent development of atrial fibrillation (AF).
  • To determine if the predictive effect of IAB on AF risk is independent of structural cardiac alterations.

Main Methods:

  • Prospective, multicentre follow-up study of subjects from the PREDICTOR population-based study.
  • Subjects were grouped based on IAB status.
  • Data collected included socio-demographics, ECGs, echocardiograms, NT-proBNP levels, with follow-up via administrative data over a mean of 6.6 years.

Main Results:

  • 1626 subjects were analyzed; 25.5% had IAB.
  • IAB alone showed a trend towards association with AF (HR=1.50, p=0.058).
  • In normal-weight subjects, IAB strongly predicted AF (HR=3.05, p=0.002), independent of confounders like left ventricular hypertrophy or NT-proBNP.

Conclusions:

  • Interatrial block (IAB) is an electrical condition that can increase the risk of developing atrial fibrillation (AF).
  • This association appears independent of underlying structural cardiac alterations, especially in normal-weight individuals.
Abstract

Keywords:
Atrial fibrillationCHA2DS2-VAScInteratrial blockLeft atrium

More Related Videos

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats05:12

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

3.8K
Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice08:05

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Published on: June 29, 2022

3.4K

Related Concept Videos

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
11.9K
Amyloid Fibrils03:03

Amyloid Fibrils

6.4K
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
147
Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
3.4K
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries
45.7K
Cable Subjected to Its Own Weight01:13

Cable Subjected to Its Own Weight

Overhead power transmission lines rely on cables to carry electricity across large distances. To ensure the stability and functionality of these lines, it is crucial to understand the shape and tension experienced by the cables under the influence of their weight.
A generalized loading function is employed to analyze a cable subjected to its own weight. This function considers the force acting along the cable's arc length rather than its projected length, providing a more accurate...
794