Related Experiment Video
Updated: Jan 28, 2026

Antibody Profiling by Luciferase Immunoprecipitation Systems LIPS
Published on: October 7, 2009
Orthognathic Surgery for Patients with Cleft Lip and Palate
Andree-Anne Roy1, Michael Alexander Rtshiladze2, Kyle Stevens3
1Department of Plastic and Reconstructive Surgery, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Abstract:
Cleft orthognathic surgery is an important component of a comprehensive cleft care plan. Applying combined orthodontic and orthognathic treatment principles to a cohort of patients with cleft lip and palate raises many challenges not encountered in conventional orthognathic care. Cleft patients share a commonality in their midfacial anatomy that is characterized by a 3-dimensionally deficient maxilla. The residual sequelae of multiple previous surgeries along with dental differences and unhealed fistulae are considerations when embarking on treatment. This article describes many of these challenges and highlights approaches that are used to address the specific needs of this special group of patients.
Related Concept Videos
Patient-centered Care
Drug Dosing: Obese Patients
Drug Dosing: Geriatric Patients
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacodynamics in Geriatric Patients: Effects of Age

