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Acute Coronary Syndrome I: Introduction01:30

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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
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Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
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Parry Romberg Syndrome.

Kelly P Schultz1, Elaine Dong1, Tuan A Truong1

  • 1Division of Plastic Surgery, Baylor College of Medicine, 6701 Fannin Street, Houston, TX 77030.

Clinics in Plastic Surgery
|March 11, 2019
PubMed
Summary
This summary is machine-generated.

Parry-Romberg syndrome causes progressive facial atrophy. Treatment involves reconstructive surgery, with fat grafting for mild cases and tissue transfer for severe cases, to restore facial symmetry.

Keywords:
Microsurgical reconstructionParry-Romberg syndromeProgressive hemifacial atrophy

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Area of Science:

  • Medical Sciences
  • Genetics and Hereditary Diseases
  • Neurology

Background:

  • Parry-Romberg syndrome (PRS), or progressive hemifacial atrophy, is a rare condition characterized by unilateral facial tissue wasting.
  • The exact cause of PRS remains unknown, highlighting a gap in current medical understanding.
  • PRS can affect skin, fat, muscle, and bone, leading to significant facial disfigurement and potential neurological complications.

Purpose of the Study:

  • To summarize the clinical presentation and management of Parry-Romberg syndrome.
  • To review the reconstructive surgical options available for patients with PRS.
  • To compare the efficacy of different surgical techniques for facial symmetry restoration.

Main Methods:

  • Literature review of Parry-Romberg syndrome cases and treatment outcomes.
  • Analysis of reconstructive techniques including autologous fat grafting and free tissue transfer.
  • Evaluation of surgical success based on aesthetic and functional results.

Main Results:

  • Patients with PRS experience progressive atrophy of facial structures, often accompanied by neurological issues.
  • Reconstructive surgery is typically performed after the condition stabilizes.
  • Serial autologous fat grafting is effective for mild to moderate soft tissue deficits.
  • Free tissue transfer is the preferred method for severe cases requiring substantial reconstruction.

Conclusions:

  • Parry-Romberg syndrome necessitates a multidisciplinary approach for management.
  • Surgical reconstruction plays a crucial role in improving the quality of life for PRS patients.
  • The choice of surgical technique depends on the severity of atrophy, with free tissue transfer being the gold standard for extensive defects.