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Assessment of Sexual Behavior of Male Mice
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Sexual Dysfunction in Men with Prediabetes.

Luca Boeri1, Paolo Capogrosso2, Eugenio Ventimiglia3

  • 1Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy; Department of Urology, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

Sexual Medicine Reviews
|March 11, 2019
PubMed
Summary
This summary is machine-generated.

Prediabetes is linked to male sexual dysfunction (SD), including erectile dysfunction (ED) and low testosterone. Screening for glucose abnormalities in men with SD is crucial for early intervention and preventing chronic illness.

Keywords:
Erectile dysfunctionMale sexual dysfunctionPrediabetesPremature ejaculationSex steroid hormones

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Area of Science:

  • Endocrinology
  • Urology
  • Men's Health

Background:

  • While diabetes mellitus (DM) is known to associate with male sexual dysfunction (SD), the link with prediabetes (preDM) is less understood.
  • Prediabetes affects a significant population, often remaining undiagnosed.
  • Existing research primarily focuses on DM, leaving a gap in understanding preDM's impact on male sexual health.

Approach:

  • A systematic review adhering to PRISMA standards was conducted.
  • Searches were performed in PubMed and Embase using terms related to male sexual dysfunction, prediabetes, and related glycemic states.
  • The review analyzed 12 studies investigating the association between prediabetes and various aspects of male sexual dysfunction.

Key Points:

  • Erectile dysfunction (ED) is more common in men with prediabetes compared to controls.
  • The severity of ED correlates with the degree of impaired glucose metabolism.
  • Prediabetes is associated with increased risk of testosterone deficiency and hypogonadism, with a reciprocal relationship observed.

Conclusions:

  • Prediabetes is strongly associated with male sexual dysfunction, underscoring its clinical significance.
  • Routine screening for glucose metabolism abnormalities in men presenting with SD is recommended.
  • Early detection of prediabetes can facilitate preventive strategies against chronic diseases.