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Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
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[Anatomo-functional study in branch retinal vein occlusion using Swept Source Optical Coherence Tomography
M Ouederni1, H Sassi1, F Nefaa1
1Hôpital Habib Thameur, 3, rue A.Ben Ayed, 1089 Tunis, Tunisie; Faculté de médecine de Tunis, Université Tunis EL MANAR, Tunisie.
Journal Francais D'Ophtalmologie
|March 12, 2019
Summary
Optical coherence tomography angiography reveals microvascular changes in branch retinal vein occlusion (BRVO). Enlargement of the foveal avascular zone (FAZ) correlates with vision loss, aiding prognosis.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Vascular Diseases
Background:
- Branch Retinal Vein Occlusion (BRVO) is a common retinal vascular disorder.
- Microvascular abnormalities are key features of BRVO.
- Assessing these changes is crucial for understanding disease progression and visual outcomes.
Purpose of the Study:
- To characterize microvascular abnormalities using OCT-angiography in eyes with BRVO.
- To quantify the foveal avascular zone (FAZ) area and capillary density.
- To establish correlations between anatomical findings and visual function.
Main Methods:
- Observational prospective study of 17 patients with unilateral BRVO.
- Analysis of microvascular changes and capillary non-perfusion in deep and superficial capillary plexuses (DCP, SCP).
- Measurement of FAZ area and capillary density using OCT-angiography and flow quantification software.
Main Results:
- Cystoid macular edema was present in 82.4% of eyes, correlating with poor visual acuity.
- Capillary non-perfusion was observed in 70.6% of eyes.
- Enlargement of the FAZ was significantly correlated with visual loss (P=0.01).
Conclusions:
- OCT-angiography is integral to diagnosing Retinal Vein Occlusion (RVO).
- FAZ area and capillary density measurements aid in predicting prognosis for BRVO patients.
- This imaging technique provides valuable insights into the microvascular landscape of BRVO.
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