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Updated: Jan 28, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
A minority of children diagnosed with Lyme disease recall a preceding tick bite
Lise E Nigrovic1, Desiree N Neville2, Fran Balamuth3
1Division of Emergency Medicine, Boston Children's Hospital, Boston, MA, United States.
Abstract:
Of 1770 children undergoing emergency department evaluation for Lyme disease, 362 (20.5%) children had Lyme disease. Of those with an available tick bite history, only a minority of those with Lyme disease had a recognized tick bite (60/325; 18.5%, 95% confidence interval 14.6-23.0%). Lack of a tick bite history does not reliably exclude Lyme disease.
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