Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Review and Preview01:10

Review and Preview

8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

11.1K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.1K
Toxic Reactions: Overview01:26

Toxic Reactions: Overview

1.9K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
1.9K
Frequency-dependent Selection01:21

Frequency-dependent Selection

23.6K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
23.6K
Predator-Prey Interactions02:39

Predator-Prey Interactions

21.4K
Predators consume prey for energy. Predators that acquire prey and prey that avoid predation both increase their chances of survival and reproduction (i.e., fitness). Routine predator-prey interactions elicit mutual adaptations that improve predator offenses, such as claws, teeth, and speed, as well as prey defenses, including crypsis, aposematism, and mimicry. Thus, predator-prey interactions resemble an evolutionary arms race.
21.4K
Ethics in Research01:56

Ethics in Research

25.5K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peri-implantitis as a potential risk factor for peri-implant oral malignancy.

Journal of the Korean Association of Oral and Maxillofacial Surgeons·2026
Same author

Feasibility of a Modified Island Groin Flap for Microsurgical Training: An Experimental Study.

The Journal of craniofacial surgery·2025
Same author

Risk factors and treatment outcomes in osteoradionecrosis in head and neck cancer patients: a retrospective analysis.

Journal of the Korean Association of Oral and Maxillofacial Surgeons·2025
Same author

Protein expression of sialolith with antrolith and tonsillolith examined by immunohistochemistry and immunoprecipitation based high performance liquid chromatography.

Scientific reports·2025
Same author

One-Piece Narrow Implants as the Last Option in Patients With Maxillofacial Deficiency.

The Journal of craniofacial surgery·2025
Same author

A deep and multi-helix flute threaded implant: a review and clinical analysis.

Journal of the Korean Association of Oral and Maxillofacial Surgeons·2025

Related Experiment Video

Updated: Jan 28, 2026

In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
07:05

In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder

Published on: June 6, 2025

549

General review of titanium toxicity.

Kyeong Tae Kim1, Mi Young Eo2, Truc Thi Hoang Nguyen2

  • 1Department of Dentistry, Dental Research Institute, Seoul National University, Seoul, South Korea.

International Journal of Implant Dentistry
|March 12, 2019
PubMed
Summary

Titanium implants, while generally safe, can cause rare adverse effects like bone loss and allergic reactions due to particle and ion release. Awareness of titanium toxicity is crucial for clinicians.

Keywords:
Titanium allergyTitanium corrosionTitanium dental implant toxicityTitanium toxicityYellow nail syndrome

More Related Videos

Assessing Disaster Resilience of Concrete with Titanium Dioxide Nanoparticles
05:45

Assessing Disaster Resilience of Concrete with Titanium Dioxide Nanoparticles

Published on: November 14, 2025

250
Digital Printing of Titanium Dioxide for Dye Sensitized Solar Cells
08:19

Digital Printing of Titanium Dioxide for Dye Sensitized Solar Cells

Published on: May 4, 2016

13.2K

Related Experiment Videos

Last Updated: Jan 28, 2026

In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
07:05

In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder

Published on: June 6, 2025

549
Assessing Disaster Resilience of Concrete with Titanium Dioxide Nanoparticles
05:45

Assessing Disaster Resilience of Concrete with Titanium Dioxide Nanoparticles

Published on: November 14, 2025

250
Digital Printing of Titanium Dioxide for Dye Sensitized Solar Cells
08:19

Digital Printing of Titanium Dioxide for Dye Sensitized Solar Cells

Published on: May 4, 2016

13.2K

Area of Science:

  • Biomaterials Science
  • Dental Implantology
  • Toxicology

Background:

  • Titanium is a widely used, generally safe biomaterial for medical and dental implants.
  • Rare adverse events associated with titanium implants necessitate a comprehensive review.
  • Existing reports on titanium-related problems are often isolated, lacking consolidated analysis.

Purpose of the Study:

  • To comprehensively review the potential toxicity of titanium materials in medical and dental applications.
  • To consolidate and analyze recent findings on titanium implant-related adverse effects.
  • To inform clinicians about rare but significant titanium toxicity issues.

Main Methods:

  • Systematic literature search using MEDLINE (PubMed), Embase, Cochrane Library, and Google Scholar.
  • Keywords included "titanium implant toxicity," "titanium implant corrosion," "titanium implant allergy," and "yellow nail syndrome."
  • Collected and categorized recent data into four key areas: titanium toxicity, alloy toxicity, implant toxicity, and related diseases.

Main Results:

  • Increasing research highlights titanium toxicity beyond environmental and basic science, extending to medical fields.
  • Titanium and alloy particles/ions from implants can cause inflammation, bone loss, and osseointegration failure.
  • Systemic deposition of titanium can lead to toxic reactions (e.g., yellow nail syndrome) and hypersensitivity-related implant failures.

Conclusions:

  • Clinicians must be vigilant regarding potential, albeit rare, adverse effects of titanium dental implants.
  • Awareness and diagnostic capability for titanium toxicity are essential despite its infrequent occurrence.
  • Further consideration of alternatives like zirconia is noted, pending long-term data.