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Regenerative Techniques for Neuraxial Back Pain: a Systematic Review
Ali K Valimahomed1, Paul Ryan Haffey2, Richard D Urman3
1Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Current Pain and Headache Reports
|March 12, 2019
Summary
Regenerative medicine shows promise for treating neuraxial back pain, particularly facet arthropathy and degenerative disc disease. Further research is needed to establish best practices and safety profiles for these advanced therapies.
Area of Science:
- Regenerative Medicine
- Neurosurgery
- Pain Management
Background:
- Regenerative modalities are increasingly recognized for their therapeutic benefits across various clinical applications.
- Neuraxial back pain, encompassing conditions like facet arthropathy and degenerative disc disease, represents a significant clinical challenge.
Purpose of the Study:
- To review key studies and current concepts regarding the application of regenerative medicine in treating neuraxial back pain.
- To summarize the efficacy of regenerative therapies for facet arthropathy and degenerative disc disease.
Main Methods:
- A systematic literature review of clinical trials published between 2015 and 2017 was conducted.
- Searches were performed using OVID, PubMed, and Google Scholar to identify relevant investigations.
- Seven selected articles were analyzed to assess the efficacy of autologous biologic treatments.
Main Results:
- Recent studies indicate that regenerative therapies demonstrate efficacy in managing neuraxial back pain.
- Promising data emerged from the analyzed articles concerning autologous biologic treatments for facet arthropathy and degenerative disc disease.
- Limitations such as small sample sizes were noted across several investigations.
Conclusions:
- Regenerative medicine holds potential as an effective treatment for neuraxial back pain.
- Further high-quality studies are essential to compare the efficacy and safety of different regenerative techniques.
- Establishing best practice standards and techniques is crucial for the advancement of this field.
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